Potential susceptibility genes in patients with stage III and IV periodontitis: A whole-exome sequencing pilot study.

Abstract excerpt

The aim of this study was to screen potential susceptibility genes using whole-exome sequencing (WES) in 15 Han Chinese patients with stage III or IV periodontitis and to evaluate the quantity and quality of genomic DNA extracted from saliva. DNA was extracted from saliva epithelial cells, quality-tested, and then subjected to WES and bioinformatics analyses. All variation loci were analyzed and interpreted...

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• DNA
• Exome
• Exome Sequencing
• Mutation
• Pilot Projects