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Article

Aging and Atherosclerosis

6 Jul 2012

Abstract excerpt

Atherosclerosis is classed as a disease of aging, such that increasing age is an independent risk factor for the development of atherosclerosis. Atherosclerosis is also associated with premature biological aging, as atherosclerotic plaques show evidence of cellular senescence characterized by reduced cell proliferation, irreversible growth arrest and apoptosis, elevated DNA damage, epigenetic modifications, and...

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PMID: 22773427
DOI: 10.1161/circresaha.111.261388

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