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WWP1 E3 ligase at the crossroads of health and disease

21 Dec 2023

Abstract excerpt

The E3 ubiquitin ligase WWP1 (WW Domain-containing E3 Ubiquitin Protein Ligase 1) is a member of the HECT (Homologous to the E6-associated protein Carboxyl Terminus) E3 ligase family. It is conserved across several species and plays crucial roles in various physiological processes, including development, cell growth and proliferation, apoptosis, and differentiation. It exerts its functions through ubiquitination...

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Genetics and Neurodevelopmental Disorders
Peptidase Inhibition and Analysis
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38129384
DOI: 10.1038/s41419-023-06380-0

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