Article
Genome-wide association study meta-analysis of blood pressure traits and hypertension in sub-Saharan African populations: an AWI-Gen study.
Nature communications - 16 Dec 2023
Singh Surina, Choudhury Ananyo, Hazelhurst Scott, Crowther Nigel J, Boua Palwendé R, Sorgho Hermann, Agongo Godfred, Nonterah Engelbert A, Micklesfield Lisa K, Norris Shane A, Kisiangani Isaac, Mohamed Shukri, Gómez-Olivé Francesc X, Tollman Stephen M, Choma Solomon, Brandenburg J-T, Ramsay Michèle
Abstract excerpt
Most hypertension-related genome-wide association studies (GWASs) focus on non-African populations, despite hypertension (a major risk factor for cardiovascular disease) being highly prevalent in Africa. The AWI-Gen study GWAS meta-analysis for blood pressure (BP)-related traits (systolic and diastolic BP, pulse pressure, mean-arterial pressure and hypertension) from three sub-Saharan African geographic regions...
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