Correlation between ESR1 and APOE gene polymorphisms and risk of osteonecrosis of the femoral head: a case-control study.

doi:10.1186/s13018-023-04447-4

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Article

Correlation between ESR1 and APOE gene polymorphisms and risk of osteonecrosis of the femoral head: a case-control study.

Journal of orthopaedic surgery and research - 15 Dec 2023

Wang Yuan, Ma Xiaoya, Guo Jinping, Li Yujie, Xiong Yuyan

Abstract excerpt

BACKGROUND: Osteonecrosis of the femoral head (ONFH) is a disease with a high disability rate, and genetic factors are closely related to its pathogenesis. This study aimed to investigate the possible correlation between ESR1 and APOE gene polymorphisms and the risk of ONFH. METHODS: In this case-control study, the potential association between three genetic variants (rs2982573 C < T, rs10872678 C < T, and...

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PMID: 38102657
DOI: 10.1186/s13018-023-04447-4
PMCID: PMC10722694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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