Article
Cancer-related SRCAP and TPR mutations in colon cancers.
Pathology, research and practice - 1 Jan 2021
Moon Seong Won, Mo Ha Yoon, Choi Eun Ji, Yoo Nam Jin, Lee Sug Hyung
Abstract excerpt
Current information suggests that SRCAP, TPR and CEACAM5 genes have cancer-related activities, but their alteration status is not well identified in colon cancer (CC). In this study, we analyzed frameshift mutations of these genes in CCs according to the microsatellite instability (MSI) status (high MSI (MSI-H) and microsatellite stable (MSS) CCs). In addition, regional difference in frameshift mutations of...
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