My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing.

doi:10.1016/j.fsigen.2013.10.012

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Article

My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing.

Forensic science international. Genetics - 1 Mar 2014

Van Neste Christophe, Vandewoestyne Mado, Van Criekinge Wim, Deforce Dieter, Van Nieuwerburgh Filip

Abstract excerpt

Forensic scientists are currently investigating how to transition from capillary electrophoresis (CE) to massive parallel sequencing (MPS) for analysis of forensic DNA profiles. MPS offers several advantages over CE such as virtually unlimited multiplexy of loci, combining both short tandem repeat (STR) and single nucleotide polymorphism (SNP) loci, small amplicons without constraints of size separation, more...

Topics

Alleles
DNA Fingerprinting
Databases, Nucleic Acid
Genetic Loci
High-Throughput Nucleotide Sequencing
Humans
Microsatellite Repeats
Polymerase Chain Reaction
Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 24528572
DOI: 10.1016/j.fsigen.2013.10.012

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