Article
Differential role of NSs genes in the neurovirulence of two genogroups of Akabane virus causing postnatal encephalomyelitis.
Archives of virology - 11 Dec 2023
Okajima Misuzu, Takenaka-Uema Akiko, Fujii Yuji, Izumi Fumiki, Kojima Isshu, Ozawa Makoto, Naitou Kiyotada, Suda Yuto, Nishiyama Shoko, Murakami Shin, Horimoto Taisuke, Ito Naoto, Shirafuji Hiroaki, Yanase Tohru, Masatani Tatsunori
Abstract excerpt
Akabane virus (AKAV) is a member of the genus Orthobunyavirus, family Peribunyaviridae. In addition to AKAV strains that cause fetal Akabane disease, which is characterized by abortion in ruminants, some AKAV strains cause postnatal infection characterized by nonsuppurative encephalomyelitis in ruminants. Here, we focused on the NSs protein, a virulence factor for most viruses belonging to the genus...
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