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Different organ and tissue tropism between Akabane virus genogroups in a mouse model.

Virus research - 1 Jun 2022

Takenaka-Uema Akiko, Matsugo Hiromichi, Ohira Kosuke, Sekine Wataru, Murakami Shin, Horimoto Taisuke

Abstract excerpt

Akabane virus (AKAV) is an etiological agent that is teratogenic to the fetus of domestic ruminants, causing a significant loss of reproduction in livestock. In East Asia, AKAV isolates form two major clusters: genogroups I and II. In recent years, genogroup I isolates have also been associated with postnatal encephalomyelitis, mainly in calves. Here, we compared the pathogenicity in mice using genogroup I Iriki...

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PMID: 35331837
DOI: 10.1016/j.virusres.2022.198752

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