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Article

Akabane virus nonstructural protein NSm regulates viral growth and pathogenicity in a mouse model.

The Journal of veterinary medical science - 1 Oct 2016

Ishihara Yukari, Shioda Chieko, Bangphoomi Norasuthi, Sugiura Keita, Saeki Kohei, Tsuda Shumpei, Iwanaga Tatsuya, Takenaka-Uema Akiko, Kato Kentaro, Murakami Shin, Uchida Kazuyuki, Akashi Hiroomi, Horimoto Taisuke

Abstract excerpt

The biological function of a nonstructural protein, NSm, of Akabane virus (AKAV) is unknown. In this study, we generated a series of NSm deletion mutant viruses by reverse genetics and compared their phenotypes. The mutant in which the NSm coding region was almost completely deleted could not be rescued, suggesting that NSm plays a role in virus replication. We next generated mutant viruses possessing various...

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Identifiers

PMID: 27181086
DOI: 10.1292/jvms.16-0140
PMCID: PMC5059365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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