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Article

A meta-analysis of the association between the ATIC 347 C/G polymorphism and methotrexate responsiveness and toxicity in rheumatoid arthritis.

Seminars in arthritis and rheumatism - 1 Feb 2024

Lee Young Ho, Song Gwan Gyu

Abstract excerpt

OBJECTIVES: The purpose of this study was to determine whether the 347 C/G polymorphism in the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase (ATIC) gene predicts the responsiveness to or toxicity of methotrexate (MTX) in patients with rheumatoid arthritis (RA). METHOD: To identify relevant publications, we searched the Medline, Embase, Cochrane, and Web of Science databases. We performed a...

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Identifiers

PMID: 38071832
DOI: 10.1016/j.semarthrit.2023.152337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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