Article
MutYH mutation carriers have increased breast cancer risk.
Cancer - 15 Apr 2012
Rennert Gad, Lejbkowicz Flavio, Cohen Ilana, Pinchev Mila, Rennert Hedy S, Barnett-Griness Ofra
Abstract excerpt
BACKGROUND: Variants of the mutY homolog gene MutYH, a DNA repair gene, are associated with increased risk of colorectal cancer; however, it remains unclear whether these variants also are associated with the risk of other cancers. The authors studied the risk of breast cancer associated with MutYH variants in a unique ethnic group of Sephardi Jews in Israel with a high prevalence of MutYH mutations. METHODS: The...
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