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Article

Causal relationship between albumin, total protein, and colorectal cancer risk: A 2-sample Mendelian randomization study.

Medicine - 17 Oct 2025

Chen Jia, Zhong Xin, Wang Fulin, Kuang Yong, Chen Jiong

Abstract excerpt

Albumin (ALB) and total protein (TP) are vital constituents of the blood, and their levels and roles in the risk of colorectal cancer (CRC) are of significance. Previous observational studies have reported correlations among ALB, TP, and CRC. However, the existence of a causal relationship between ALB and CRC in European populations has not been adequately investigated and the causal link between TP and CRC...

Read the complete abstract on PubMed

Topics

Humans
Colorectal Neoplasms
Mendelian Randomization Analysis
Genome-Wide Association Study
Polymorphism, Single Nucleotide
Risk Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Female

Serum Albumin

Blood Proteins

Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 41189249
DOI: 10.1097/MD.0000000000045229
PMCID: PMC12537268

Genes

ALB

Provenance

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