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Article

A novel piwi-interacting RNA associates with type 2-high asthma phenotypes.

The Journal of allergy and clinical immunology - 1 Mar 2024

Li Jiang, Hong Xiaoning, Jiang Mingye, Kho Alvin T, Tiwari Anshul, Wang Alberta L, Chase Robert P, Celedón Juan C, Weiss Scott T, McGeachie Michael J, Tantisira Kelan G

Abstract excerpt

BACKGROUND: Piwi-interacting RNAs (piRNAs), comprising the largest noncoding RNA group, regulate transcriptional processes. Whether piRNAs are associated with type 2 (T2)-high asthma is unknown. OBJECTIVE: We sought to investigate the association between piRNAs and T2-high asthma in childhood asthma. METHODS: We sequenced plasma samples from 462 subjects in the Childhood Asthma Management Program (CAMP) as the...

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Identifiers

PMID: 38056635
DOI: 10.1016/j.jaci.2023.10.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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