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Article

Novel eosinophilic gene expression networks associated with IgE in two distinct asthma populations

14 Aug 2018

Abstract excerpt

BACKGROUND: Asthma represents a significant public health burden; however, novel biological therapies targeting immunoglobulin E (IgE)-mediated pathways have widened clinical treatment options for the disease. OBJECTIVE: In this study, we sought to identify gene transcripts and gene networks involved in the determination of serum IgE levels in people with asthma that can help inform the development of novel...

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PMID: 30107053
DOI: 10.1111/cea.13249

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