Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle.

Nature communications - 5 Dec 2023

Zhao Yang, Zheng Zhizhong, Zhang Zhihui, Xu Yandong, Hillpot Eric, Lin Yifei S, Zakusilo Frances T, Lu J Yuyang, Ablaeva Julia, Biashad Seyed Ali, Miller Richard A, Nevo Eviatar, Seluanov Andrei, Gorbunova Vera

Abstract excerpt

Hyaluronic acid is a major component of extracellular matrix which plays an important role in development, cellular response to injury and inflammation, cell migration, and cancer. The naked mole-rat (Heterocephalus glaber) contains abundant high-molecular-mass hyaluronic acid in its tissues, which contributes to this species' cancer resistance and possibly to its longevity. Here we report that abundant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hyaluronic Acid
Share to Longevity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammals

Share to Mutation

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 38052795
DOI: 10.1038/s41467-023-43623-2
PMCID: PMC10698142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle.PMID 38052795Read ↗

The material properties of naked mole-rat hyaluronanSemantic proximity Read ↗

Biochemical, Cellular, Physiological, and Pathological Consequences of Human Loss of N-Glycolylneuraminic Acid.Semantic proximity Read ↗

CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistanceSemantic proximity Read ↗

Harnessing Longevity Genes for Lifespan Extension: Insights from Naked Mole RatsSemantic proximity Read ↗

Genetic Deficiencies of Hyaluronan DegradationSemantic proximity Read ↗

Mammalian hyaluronan synthases: investigation of functional relationships in vivo.Semantic proximity Read ↗

Expression of the naked mole-rat transgene for <i>Has2</i> improved health span in C57Bl/6 mice, but it did not attenuate age-related hearing lossSemantic proximity Read ↗

Advanced Glycation End-Products as Markers of Aging and Longevity in the Long-Lived Ansell’s Mole-Rat (Fukomys anselli)Semantic proximity Read ↗

Fifty-kDa Hyaluronic Acid Upregulates Some Epidermal Genes without Changing TNF-α Expression in Reconstituted EpidermisSemantic proximity Read ↗

Naked Mole-Rat Cells are Susceptible to Malignant Transformation by <i>SV40LT</i> and Oncogenic RasSemantic proximity Read ↗

Hyaluronic Acid of Low Molecular Weight Triggers the Invasive "Hummingbird" Phenotype on Gastric Cancer Cells.Semantic proximity Read ↗

The Effects of the Molecular Weights of Hyaluronic Acid on the Immune ResponsesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.