Article
Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor
1 Jun 2010
Abstract excerpt
Primary human keratinocytes are useful for studying the pathogenesis of many different diseases of the cutaneous and mucosal epithelia. In addition, they can form organotypic tissue equivalents in culture that can be used as epidermal autografts for wound repair as well as for the delivery of gene therapy. However, primary keratinocytes have a finite lifespan in culture that limits their proliferative capacity...
Topics
Join the communities discussing this publication.