Article
A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs.
Journal of translational medicine - 1 Dec 2023
Xie Jianzhu, Hu Binjie, Gong Yanping, He Sijia, Lin Jun, Huang Qian, Cheng Jin
Abstract excerpt
BACKGROUND: Liquid biopsy provides a non-invasive approach that enables detecting circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) using blood specimens and theoretically benefits early finding primary tumor or monitoring treatment response as well as tumor recurrence. Despite many studies on these novel biomarkers, their clinical relevance remains controversial. This study aims to investigate the...
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