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Article

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.

Journal of the American Heart Association - 5 Dec 2023

Liu Minghua, Khasiyev Farid, Sariya Sanjeev, Spagnolo-Allende Antonio, Sanchez Danurys L, Andrews Howard, Yang Qiong, Beiser Alexa, Qiao Ye, Thomas Emy A, Romero Jose Rafael, Rundek Tatjana, Brickman Adam M, Manly Jennifer J, Elkind Mitchell Sv, Seshadri Sudha, Chen Christopher, Hilal Saima, Wasserman Bruce A, Tosto Giuseppe, Fornage Myriam, Gutierrez Jose

Abstract excerpt

BACKGROUND: Brain arterial diameters (BADs) are novel imaging biomarkers of cerebrovascular disease, cognitive decline, and dementia. Traditional vascular risk factors have been associated with BADs, but whether there may be genetic determinants of BADs is unknown. METHODS AND RESULTS: The authors studied 4150 participants from 6 geographically diverse population-based cohorts (40% European, 14% African, 22%...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 10

Share to BAD gene

Share to Genetic Associations and Epidemiology

Share to Genetic Predisposition to Disease

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Share to Methyltransferases

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 38038215
DOI: 10.1161/JAHA.123.030935
PMCID: PMC10727334

Genes

BAD
CNNM2
AS3MT
NT5C2
ADAP1
TCF25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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