Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

30 Nov 2023

Abstract excerpt

BACKGROUND: Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as a tumor suppressor in ovarian cancer cells and its loss accelerated formation of carcinomatosis and drove tumor progression in an ovarian cancer mouse model. The goal of this study is to identify specific signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38037081
DOI: 10.1186/s13048-023-01312-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cellsPMID 38037081Read ↗

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cellsSemantic proximity Read ↗

CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinomaSemantic proximity Read ↗

CBX7 inhibits breast tumorigenicity through DKK‐1‐mediated suppression of the Wnt/β‐catenin pathwaySemantic proximity Read ↗

Integrated bioinformatics investigation and experimental validation reveals the clinical and biological significance of chromobox family in breast cancerSemantic proximity Read ↗

Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancerSemantic proximity Read ↗

Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARCSemantic proximity Read ↗

ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathwaySemantic proximity Read ↗

The molecular mechanism of serum exosome miR-133b regulating the proliferation and apoptosis of vaginal smooth muscle cells by targeting AXUD1 to regulate Wnt / β-catenin signaling pathwaySemantic proximity Read ↗

Role of the chromobox protein CBX7 in lymphomagenesis.Semantic proximity Read ↗

CBX8 Suppresses Tumor Metastasis via Repressing Snail in Esophageal Squamous Cell CarcinomaSemantic proximity Read ↗

Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos.Semantic proximity Read ↗

Role of cystathionine beta synthase in lipid metabolism in ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.