Article

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

2023-11-10

Abstract excerpt

<h4>Background</h4> Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as a tumor suppressor in ovarian cancer cells and its loss accelerated formation of carcinomatosis and drove tumor progression in an ovarian cancer mouse model. The goal of this study is to identify specific si...

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Literature Corpus work: e28e2ff4-5702-5a3f-9c23-85a155b95253
DOI: 10.1101/2023.11.07.566022

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