Article
Plasma thrombin-activatable fibrinolysis inhibitor and the 1040C/T polymorphism are risk factors for diabetic kidney disease in Chinese patients with type 2 diabetes.
PeerJ - 1 Jan 2023
Huang Qinghua, Feng Dujin, Pan Lianlian, Wang Huan, Wu Yan, Zhong Bin, Gong Jianguang, Lin Huijun, Fei Xianming
Abstract excerpt
Background: Inflammatory and hemostatic disorders in diabetic microangiopathy (DMA) can be linked to thrombin-activatable fibrinolysis inhibitor (TAFI) and its own gene polymorphisms. Thus, the study aimed to investigate the associations of plasma TAFI and gene polymorphisms with DMA in Chinese patients with type 2 diabetes (T2D). Methods: Plasma TAFI of 223 patients with T2D was measured, and the genotypes and...
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