Article
Decreased plasma kallikrein activity is associated with reduced kidney function in individuals with type 1 diabetes.
Diabetologia - 1 Jul 2020
Härma Mari-Anne, Dahlström Emma H, Sandholm Niina, Forsblom Carol, Groop Per-Henrik, Lehto Markku
Abstract excerpt
AIMS/HYPOTHESIS: Plasma kallikrein is the central mediator of the plasma kallikrein-kinin system, which is involved both in vascular control and thrombin formation cascades. The plasma kallikrein-kinin system has also been considered protective in pathological conditions, but the impact of plasma kallikreins on diabetic nephropathy remains unknown. The objective of this cross-sectional study was to explore the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
