Article
Association of plasminogen activator inhibitor-1 4G/4G genotype and type 2 diabetic nephropathy in Chinese patients.
Kidney international - 1 Feb 2000
Wong T Y, Poon P, Szeto C C, Chan J C, Li P K
Abstract excerpt
BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is a key regulator of fibrinolytic pathway and extracellular matrix (ECM) turnover. Because diabetic nephropathy is characterized by the presence of basement membrane thickening and mesangial expansion, we examined the role of PAI-1 gene polym...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
