Article
A missense mutation in Lama3 causes androgen alopecia.
Scientific reports - 27 Nov 2023
Ji Zhong-Hao, Ren Wen-Zhi, He Song, Wu Hong-Yu, Yuan Bao, Chen Jian, Jin Hong-Juan
Abstract excerpt
Hair loss disorders such as androgenetic alopecia have caused serious disturbances to normal human life. Animal models play an important role in exploring pathogenesis of disease and evaluating new therapies. NIH hairless mice are a spontaneous hairless mouse discovered and bred in our laboratory. In this study, we resequenced the genomes of NIH normal mice and NIH hairless mice and obtained 3,575,560...
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