Article
Candidate gene analysis of asthma in a population of Arab descent: a case-control study in Jordan.
Personalized medicine - 1 Jan 2017
Almomani Basima A, Al-Eitan Laith N, Samrah Shaher M, Al-Quasmi Mohammed N, McKnight Amy J
Abstract excerpt
AIM: To evaluate whether SNPs (n = 15) in ten candidate genes (ADRB2, ADH5, ARGI, CRHR1, STIP1, LTA4H, LTC4S, ALOX5, ABCC1 and OATP2B1) are associated with asthma in Jordanian population of Arab descent. METHODS: A case-control study included 245 adult asthmatics and 249 controls. RESULTS: Significant genetic association was identified at the rs2236647 (T/C) SNP in STIP1 and risk of asthma (p < 0.001). The C...
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