Article
Polymorphisms in LRP2 and CUBN genes and their association with serum vitamin D levels and sleep apnea.
Sleep & breathing = Schlaf & Atmung - 1 May 2024
Anatolou Dimitra, Steiropoulos Paschalis, Zissimopoulos Athanasios, Chadia Konstantina, Archontogeorgis Kostas, Kolios George, Manolopoulos Vangelis G, Ragia Georgia
Abstract excerpt
PURPOSE: Vitamin D deficiency has been associated with the occurrence of obstructive sleep apnea syndrome (OSAS). Megalin (LRP2) and cubilin (CUBN) are implicated in vitamin D metabolism, whereas LRP2 and CUBN polymorphisms have been previously associated with variable serum vitamin D levels. The present study aimed to evaluate the role of LRP2 rs2228171 c.8614C > T and CUBN rs1801222 c.758A > G polymorphisms in...
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