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Nidogen-1/NID1 Function and Regulation during Progression and Metastasis of Colorectal Cancer

7 Nov 2023

Abstract excerpt

We have previously shown that the extracellular matrix and basement membrane protein Nidogen1 (NID1) is secreted by more malignant, mesenchymal-like CRC cells and induces the epithelial–mesenchymal transition (EMT) and promotes the migration and invasion of less malignant, epithelial-like CRC cells. Here, we performed a comprehensive bioinformatics analysis of multiple datasets derived from CRC patients and...

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PMID: 38001576
DOI: 10.3390/cancers15225316

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