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Identification of mitophagy‐associated proteins profile as potential plasma biomarkers of idiopathic Parkinson's disease

21 Nov 2023

Abstract excerpt

BACKGROUND: Despite extensive work to identify diagnostic plasma markers for Parkinson's disease (PD), there are still no accepted and validated surrogate biomarkers. Mitophagy-associated proteins (MAPs), including PTEN-induced putative kinase 1 (PINK1), Parkin, phosphoglycerate mutase 5 (PGAM5), BCL2 interacting protein 3 (BNIP3), and phosphorylated-TBK1 (p-TBK1), are, to our best knowledge, not well studied as...

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PMID: 37990436
DOI: 10.1111/cns.14532

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