Article
Prevention of transgenerational transmission of disease susceptibility through perinatal intervention.
Endocrine journal - 28 Mar 2024
Nemoto Takahiro, Sagawa Norimasa
Abstract excerpt
The observational findings of Barker's original epidemiological studies were generalized as the Barker hypothesis and extended as the Developmental Origins of Health and Disease (DOHaD) theory. Barker et al. proposed that low birthweight (LBW) was associated with the occurrence of various noncommunicable diseases (NCDs) later in life. In other words, LBW itself is associated with the development of NCDs. This led...
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