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The developmental origins of adult disease (Barker) hypothesis

25 Jan 2006

Abstract excerpt

Many studies have provided evidence for the hypothesis that size at birth is related to the risk of developing disease in later life. In particular, links are well established between reduced birthweight and increased risk of coronary heart disease, diabetes, hypertension and stroke in adulthood. These relationships are modified by patterns of postnatal growth. The most widely accepted mechanisms thought to...

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PMID: 16441686
DOI: 10.1111/j.1479-828x.2006.00506.x

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