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Developmental origin of chronic diseases: toxicological implication

1 Jan 2008

Abstract excerpt

Human epidemiological and experimental animal studies show that suboptimal environments in fetal and neonatal life exerts a profound influence on physiological function and risk of disease in adult life. The molecular, cellular, metabolic, endocrine and physiological adaptations to intrauterine nutritional conditions result in permanent alterations of cellular proliferation and differentiation of tissues and...

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PMID: 21218103
DOI: 10.2478/v10102-010-0029-8

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