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Article

Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment.

Reproduction (Cambridge, England) - 1 Dec 2014

El Hajj Nady, Schneider Eberhard, Lehnen Harald, Haaf Thomas

Abstract excerpt

The phenomenon that adverse environmental exposures in early life are associated with increased susceptibilities for many adult, particularly metabolic diseases, is now referred to as 'developmental origins of health and disease (DOHAD)' or 'Barker' hypothesis. Fetal overnutrition and undernutrition have similar long-lasting effects on the setting of the neuroendocrine control systems, energy homeostasis, and...

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Identifiers

PMID: 25187623
DOI: 10.1530/REP-14-0334
PMCID: PMC4241689

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Source receipt: pubmed, retrieved 7 Sept 2026.

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