Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Poly(ADP-ribosyl)ating enzymes coordinate changes in the expression of metabolic genes with developmental progression.

Scientific reports - 20 Nov 2023

Bordet Guillaume, Bamgbose Gbolahan, Tulin Alexei V

Abstract excerpt

Metabolism, known to be temporally regulated to meet evolving energy demands, plays a crucial role in shaping developmental pace. Recent studies have demonstrated that two key proteins PARP1 and PARG play a regulatory role in the transcription of both morphogenic and metabolic genes. Intriguingly, in Drosophila, the depletion of PARP1 or PARG proteins causes a developmental arrest before pupation, resulting in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Glycoside Hydrolases
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Poly(ADP-ribose) Polymerases

Source

Open in PubMed Open full text

Identifiers

PMID: 37985852
DOI: 10.1038/s41598-023-47691-8
PMCID: PMC10661653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Poly(ADP-ribosyl)ating enzymes coordinate changes in the expression of metabolic genes with developmental progression.PMID 37985852Read ↗

Poly(ADP-ribosyl)ating pathway regulates development from stem cell niche to longevity control.Semantic proximity Read ↗

Drosophila poly(ADP-ribose) glycohydrolase mediates chromatin structure and SIR2-dependent silencing.Semantic proximity Read ↗

Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster.Semantic proximity Read ↗

A systematic analysis of the PARP protein family identifies new functions critical for cell physiology.Semantic proximity Read ↗

PARG Inhibitors and Functional PARG Inhibition Models.Semantic proximity Read ↗

Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.Semantic proximity Read ↗

Novel insights into PARPs in gene expression: regulation of RNA metabolismSemantic proximity Read ↗

Poly(ADP-ribosyl)ation Acts in the DNA Demethylation of Mouse Primordial Germ Cells Also with DNA Damage-Independent RolesSemantic proximity Read ↗

TaqMan Multiplex qPCR Method to Genotype PARG Knockout Mice.Semantic proximity Read ↗

The histone methyltransferase G9a regulates tolerance to oxidative stress–induced energy consumptionSemantic proximity Read ↗

Distribution of protein poly(ADP-ribosyl)ation systems across all domains of lifeSemantic proximity Read ↗

Poly (ADP-ribose) glycohydrolase regulates retinoic acid receptor-mediated gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.