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Article

Poly(ADP-ribosyl)ating pathway regulates development from stem cell niche to longevity control.

Life science alliance - 1 Mar 2022

Bordet Guillaume, Kotova Elena, Tulin Alexei V

Abstract excerpt

The regulation of poly(ADP-ribose) polymerase, the enzyme responsible for the synthesis of homopolymer ADP-ribose chains on nuclear proteins, has been extensively studied over the last decades for its involvement in tumorigenesis processes. However, the regulation of poly(ADP-ribose) glycohydrolase (PARG), the enzyme responsible for removing this posttranslational modification, has attracted little attention....

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Identifiers

PMID: 34949666
DOI: 10.26508/lsa.202101071
PMCID: PMC8739260

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Poly(ADP-ribosyl)ating pathway regulates development from stem cell niche to longevity control.PMID 34949666Read ↗

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