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Article

Evidence of positive selection of genetic variants associated with PCOS

1 Nov 2023

Abstract excerpt

STUDY QUESTION: Was polycystic ovary syndrome (PCOS), which impairs fertility and adheres to the evolutionary paradox, subject to evolutionary selection during ancestral times and did rapidly diminish in prevalence? SUMMARY ANSWER: This study strengthened the hypothesis that positive selection of genetic variants occurred and may account for the high prevalence of PCOS observed today. WHAT IS KNOWN ALREADY: PCOS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37982420
DOI: 10.1093/humrep/dead106

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