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Article

Effects of alcohol concentration and temperature on the dynamics and stability of mutant Staphylococcal lipase.

Journal of biomolecular structure & dynamics - 1 Jan 2025

Ong Shir Nee, Kamarudin Nor Hafizah Ahmad, Shariff Fairolniza Mohd, Noor Noor Dina Muhd, Ali Mohd Shukuri Mohamad, Rahman Raja Noor Zaliha Raja Abd

Abstract excerpt

The stability and activity of lipase in organic media are important parameters in determining how quickly biocatalysis proceeds. This study aimed to examine the effects of two commonly used alcohols in industrial applications, methanol (MtOH) and ethanol (EtOH) on the conformational stability and catalytic activity of G210C lipase, a laboratory-evolved mutant of Staphylococcus epidermidis AT2 lipase. Simulation...

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Source

Identifiers

PMID: 37968883
DOI: 10.1080/07391102.2023.2282177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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