Article
Deep sequencing reveals recurrent somatic mutations and distinct molecular subgroups in gastric cancer in Mizo population, North East India.
Genomics - 1 Nov 2023
Chakraborty Payel, Kurkalang Sillarine, Ghatak Souvik, Das Subrata, Palodhi Arindam, Sarkar Sumanta, Dhar Ranjan, Chenkual Saia, Pachuau Lalawmpuii, Zohmingthanga John, Pautu Jeremy L, Zomuana Thomas, Lalruatfela Sailo Tlau, Zothanzama John, Kumar Nachimuthu Senthil, Maitra Arindam
Abstract excerpt
In India, Mizoram has the highest incidence of gastric cancer (GC) which might be associated with environmental factors such as diet, Helicobacter pylori (H.pylori) and Epstein-Barr virus (EBV) infections, and somatic genomic alterations. We performed PCR cum sequencing and fragment analysis for detection of H. pylori/EBV infection and microsatellite Instability (MSI) in GC patients (N = 68). Somatic mutations...
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