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Analysis of CD74 Occurrence in Oncogenic Fusion Proteins

5 Nov 2023

Abstract excerpt

CD74 is a type II cell surface receptor found to be highly expressed in several hematological and solid cancers, due to its ability to activate pathways associated with tumor cell survival and proliferation. Over the past 16 years, CD74 has emerged as a commonly detected fusion partner in multiple oncogenic fusion proteins. Studies have found CD74 fusion proteins in a range of cancers, including lung...

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PMID: 37958963
DOI: 10.3390/ijms242115981

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