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CD74 as a prognostic and M1 macrophage infiltration marker in a comprehensive pan-cancer analysis

7 Apr 2024

Abstract excerpt

CD74 is a type-II transmembrane glycoprotein that has been linked to tumorigenesis. However, this association was based only on phenotypic studies, and, to date, no in-depth mechanistic studies have been conducted. In this study, combined with a multi-omics study, CD74 levels were significantly upregulated in most cancers relative to normal tissues and were found to be predictive of prognosis. Elevated CD74...

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PMID: 38582956
DOI: 10.1038/s41598-024-58899-7

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