Article
Contribution of Telomere Length to Systemic Sclerosis Onset: A Mendelian Randomization Study.
International journal of molecular sciences - 25 Oct 2023
Rodriguez-Martin Inmaculada, Villanueva-Martin Gonzalo, Guillen-Del-Castillo Alfredo, Ortego-Centeno Norberto, Callejas José L, Simeón-Aznar Carmen P, Martin Javier, Acosta-Herrera Marialbert
Abstract excerpt
Although previous studies have suggested a relationship between telomere shortening and systemic sclerosis (SSc), the association between these two traits remains poorly understood. The objective of this study was to assess the causal relationship between telomere length in leukocytes (LTL) and SSc using the two-sample Mendelian randomization approach, with the genome-wide association study data for both LTL and...
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