Article
Association between telomere length in peripheral blood leukocytes and risk of ischemic stroke in a Han Chinese population: a linear and non-linear Mendelian randomization analysis.
Journal of translational medicine - 12 Oct 2020
Cao Weijie, Zheng Deqiang, Zhang Jie, Wang Anxin, Liu Di, Zhang Jinxia, Singh Manjot, Maranga Isinta Elijah, Cao Mingyang, Wu Lijuan, Song Manshu, Wang Wei, Wang Youxin
Abstract excerpt
BACKGROUND: Many contradictory conclusions pertaining to the telomere length in peripheral leukocyte chromosomes as a potential biomarker for ischemic stroke (IS) risk have been reported by the various observational studies in previous years. This study aims to investigate whether the leukocyte telomere length is associated with an increased IS risk or not, based on the Mendelian randomization (MR) approach....
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