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Article

Telomere Length and Development of Systemic Lupus Erythematosus: A Mendelian Randomization Study.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Dec 2022

Wang Xu-Fan, Xu Wen-Jing, Wang Fei-Fei, Leng Rui, Yang Xiao-Ke, Ling Hua-Zhi, Fan Yin-Guang, Tao Jin-Hui, Shuai Zong-Wen, Zhang Li, Ye Dong-Qing, Leng Rui-Xue

Abstract excerpt

OBJECTIVE: Previous observational studies demonstrated that a subset of patients with systemic lupus erythematosus (SLE) have markedly short telomere length in leukocytes. This study was undertaken to test whether leukocyte telomere length is causally associated with risk of SLE. METHODS: A 2-sample Mendelian randomization (MR) analysis was conducted to estimate causality of telomere length on SLE in European...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35830513
DOI: 10.1002/art.42304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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