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Article

Telomere length and its association with systemic lupus erythematosus in an Asian population: A Mendelian randomization study.

Lupus - 1 Sept 2023

Zhang Yasi, Zhu Yanan, Ye Meijie, Mao Yong, Zhan Yiqiang

Abstract excerpt

OBJECTIVES: To investigate whether shorter telomere length is a causal risk factor for systemic lupus erythematosus (SLE) in the Asian population. METHODS: We applied the two-sample Mendelian randomization (MR) method to the pooled statistics from a genome-wide association study (GWAS) of 6,707 SLE cases and 16,047 controls. We selected nine single-nucleotide polymorphisms (SNPs) with genome-wide significance as...

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PMID: 37596879
DOI: 10.1177/09612033231195953

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