Article
Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis
13 Nov 2023
Abstract excerpt
Besides the regulation of many cellular pathways, ubiquitination is important for defense against invading pathogens. Some intracellular bacteria have evolved deubiquitinase (DUB) effector proteins, which interfere with the host ubiquitin system and help the pathogen to evade xenophagy and lysosomal degradation. Most intracellular bacteria encode one or two DUBs, which are often linkage-promiscuous or...
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