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LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth

15 Mar 2018

Abstract excerpt

The intracellular bacterial pathogen, Legionella pneumophila, establishes the replicative niche as a result of the actions of a large array of effector proteins delivered via the Legionella Type 4 secretion system. Many effector proteins are expected to be involved in biogenesis and regulation of the Legionella-containing vacuole (LCV) that is highly decorated with ubiquitin. Here, we identified a Legionella...

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PMID: 29543380
DOI: 10.1111/cmi.12840

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