Article
Protective effect of uridine on atrial fibrillation: a Mendelian randomisation study.
Scientific reports - 10 Nov 2023
Xu Xintian, Zhang Xiaoyu, Cheng Shiyao, Li Qinglang, Chen Cai, Ouyang Mao
Abstract excerpt
Uridine, a pyrimidine nucleoside, is crucial in the synthesis of metabolites. According to observational studies, a higher plasma uridine level is associated with a lower risk of atrial fibrillation (AF). However, the casual relationship between uridine and AF is still unknown. In this study, we used the Mendelian randomisation (MR) approach to explore causality. Three genetic variants associated with uridine...
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