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Type 2 diabetes and inflammatory bowel disease: a bidirectional two-sample Mendelian randomization study

1 Mar 2024

Abstract excerpt

To investigate the association between T2DM and IBD by bidirectional two-sample Mendelian randomization (MR) to clarify the casual relationship. Independent genetic variants for T2DM and IBD were selected as instruments from published genome-wide association studies (GWAS), mainly in European ancestry. Instrumental variables (IVs) associated with T2DM and IBD were extracted separately from the largest GWAS...

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PMID: 38429331
DOI: 10.1038/s41598-024-55869-x

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