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Article

Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis.

Journal of immunology research - 1 Jan 2022

Ding Yang, Yang Shengyi, Fan Shasha, Tang Yi, Teng Yan, Tao Xiaohua, Lu Wei

Abstract excerpt

Background: Vitamin D deficiency is common in patients with systemic lupus erythematosus (SLE). Observational studies have reported that it is associated with SLE. In this bidirectional Mendelian randomization (MR) study, we explored the genetic association between serum vitamin D (VD) levels and SLE using two models. Methods: Genetic variants associated with vitamin D (n = 304,181), 25-hydroxyvitamin D levels (n...

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Source

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Identifiers

PMID: 36189146
DOI: 10.1155/2022/8689777
PMCID: PMC9519279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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