Article
METTL16 predicts a favorable outcome and primes antitumor immunity in pancreatic ductal adenocarcinoma
9 Sept 2022
Abstract excerpt
Pancreatic carcinogenesis is a complicated and multi-step process. It is substantially assisted by N6-methyladenosine (m6A) RNA modification, especially when mutations of driver genes (KRAS, TP53, CDKN2A, and SMAD4) occur. However, the underlying mechanism remains obscure. In this research, we identified m6A regulators as potential biomarkers when mutations of driver genes occur, and investigated the role of...
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